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DOSAGE AND ADMINISTRATION
Doses vary widely, from 12.5 mcg per hour to 100 mcg per hour or more. The initial safe dose is determined by the amount of pain medicine that has been previously required in a typical 24-hour period.The dose should not be increased more often than every 3 days after the initial dose or every 6 days thereafter
Use intact patches. Never cut the patches or use damaged patches (could result in an overdose)
Apply patches only on skin without cuts or sores. Do not shave the area before applying the patch.
Put the patch on the chest, back, flank (sides of the waist), or upper arm in a place where there is no hair.
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Because serious or life-threatening hypoventilation could occur, DURAGESIC® (fentanyl transdermal system) is contraindicated:
- in patients who are not opioid-tolerant
- in the management of acute pain or in patients who require opioid analgesia for a short period of time
- in the management of post-operative pain, including use after out-patient or day surgeries, (e.g., tonsillectomies)
- in the management of mild pain
- in the management of intermittent pain (e.g., use on an as-needed basis.
- in situations of significant respiratory depression, especially in
unmonitored settings where there is a lack of resuscitative equipment
- in patients who have acute or severe bronchial asthma
DURAGESIC® (fentanyl transdermal system) is contraindicated in patients who have or are suspected of having paralytic ileus.
DURAGESIC® (fentanyl transdermal system) is contraindicated in patients with known hypersensitivity to fentanyl or any components of this product.
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While using DURAGESIC® DO NOT: While using DURAGESIC® DO NOT: Take hot baths or sunbathe, use hot tubs, saunas, heating pads, electric blankets, heated waterbeds, or tanning lamps, or engage in exercise that increases your body temperature. These can cause an overdose that can lead to death. DO NOT drive or operate heavy machinery, until you know how DURAGESIC® affects you. DURAGESIC® can make you sleepy, dizzy, or lightheaded. DO NOT drink alcohol or use prescription or over-the-counter medicines that contain alcohol. Using products containing alcohol during treatment with DURAGESIC® may cause you to overdose and die.
Do not put a DURAGESIC patch on skin that is very oily, burned, broken out, cut, irritated, or damaged in any way. Avoid sensitive areas or those that move around a lot. If there is hair, do not shave (shaving irritates the skin). Instead, clip the hair as close to the skin as possible. Talk to your healthcare provider if you have questions about skin application sites.
A long-acting (extended-release) opioid pain medicine that can put you at risk for overdose and death. Even if you take your dose correctly as prescribed you are at risk for opioid addiction, abuse, and misuse that can lead to death. Not for use to treat pain that is not around-the-clock·.
DURAGESIC® patches are intended for transdermal use (on intact skin) only. Using damaged or cut DURAGESIC® patches can lead to the rapid release of the contents of the DURAGESIC® patch and absorption of a potentially fatal dose of fentanyl. The safety of DURAGESIC® (fentanyl transdermal system) has not been established in children under 2 years of age. DURAGESIC® should be administered to children only if they are opioid-tolerant and 2 years of age or older. More Info
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